Collagen cross-linking (UXL) in Sydney to help strengthen thinning corneas

This treatment uses riboflavin eye drops and ultraviolet light to strengthen corneal collagen, which may help slow or halt progression in suitable patients with keratoconus or corneal thinning

Collagen Cross Linking (UXL) in Sydney to help strengthen thinning corneas

This treatment uses riboflavin eye drops and ultraviolet light to strengthen corneal collagen, which may help slow or halt progression in suitable patients with keratoconus or corneal thinning

With collagen cross-linking, patients may slow the progression of keratoconus or corneal thinning

Discover how this eye treatment works, who it may suit, and what to expect before, during, and after treatment

What is Collagen cross-linking?

Collagen cross-linking is a new technique designed to treat patients with thinning corneas or suffering from keratoconus. The objective of the surgery is to strengthen the cornea to slow down or halt corneal thinning, it is not a cure for the disease.

This procedure has been pioneered in Australia by our principal surgeon Dr John Males. It is hoped this technique will delay or prevent the need for a corneal transplant.

  • If you have been diagnosed with thinning corneas
  • If you suffer from keratoconus and your vision is impacted
  • You will require a full examination to test your suitability for the procedure
  • You need to have notable progression to the keratoconus for this procedure to be suitable.

Laser vision correction has traditionally not been available for those with keratoconus. This new technique combines Collagen cross-linking with topography guided laser vision. You will first require a full examination to test your suitability for the procedure. This includes a test for refraction, two forms of corneal topography (mapping the cornea), and including scanning with a Pentacam and Sirius corneal topographers.

The treatment is designed to reduce the strength of glasses or contact lenses, and unlike regular laser vision correction, you may still require glasses or contact lenses to obtain the best vision possible, although the strength of the prescription is reduced in most cases.

Read a detailed clinical article on this procedure.

  • The upper most layer of the cornea (epithelium) is removed
  • Riboflaven (Vitamin) B2 drops are instilled in the eye for 30 minutes
  • A controlled amount of ultraviolet light (UVA) is used to increase the natural anchors or bonds within the cornea to stop it from bulging out and becoming steep and irregular. The process produces a biomechanical stabilisation of the cornea.

Like any eye procedure, collagen cross-linking has risks. These can include pain, light sensitivity, delayed healing, infection, corneal haze, sterile infiltrates, scarring, and in rare cases reduced vision. Some patients may also experience temporary worsening of vision while the surface heals. The exact risk profile depends on the technique used, the thickness of the cornea, and the eye being treated.

Because the goal is to stabilise the cornea rather than guarantee visual improvement, a proper consultation should include a balanced discussion of benefits, limitations, and risks.

  • There is some discomfort associated or the first few days after the treatment, pain relieving tablets are given to assist with this phase of healing. A “bandage” contact lens is placed in the operated eye for the comfort of the patient. This lens is removed after 4-5 days, the vision is generally quite hazy and blurry shortly after surgery and takes several weeks to settle
  • The outcome is dependent on how advanced the keratoconus is. The treatment is designed to strengthen the cornea and halt the progression of keratoconus. It is not a cure for the condition.

Clear guidance for your eye care journey

Eye treatment options can vary from person to person. We help you understand what is happening and what care may be right for you

Step 1: REACH OUT

The first step is to book an assessment so your symptoms, concerns, or vision goals can be discussed with the clinic. Give our friendly team a call or use our easy online calendar to book a free assessment.

Step 2: WE’LL MEET

At your visit, our refractive surgeons will examine your eyes, explain the findings, and talk through the treatment options that may be appropriate for your condition and needs.

Step 3: ENJOY COMFORT

After treatment, the aim is to help you see more clearly, feel more comfortable, and manage your eye health with greater confidence. Depending on your condition and treatment plan, this may make daily life feel easier and more manageable.

Find comfort and clarity for your eyes

Take our free online assessment to discover the next step toward healthier, more comfortable vision

Hi, I’m Dr John Males

I’m the owner and principal surgeon at Envision Eye Centre, specialising in laser vision correction, cataract, and corneal surgery. With over 15 years’ experience, I’ve been involved in introducing advanced procedures such as SMILE® and laser-assisted cataract surgery in Australia. I’ve held leadership roles at St Vincent’s Hospital and Sydney Eye Hospital, and I continue to contribute to teaching and research through the University of Sydney. My focus is always on delivering safe, precise, and personalised care, using the latest technology to help patients achieve the best possible visual outcomes.

Dr John Males

M.B B. Sc. (Med)(Hons) MMed (Clin Epi) FRANZCO